Effects of cyclopeptide C*HSDGIC* from the cyclization of PACAP (1-5) on the proliferation and UVB-induced apoptosis of the retinal ganglion cell line RGC-5

► Determination of PAC1 expression in normal RGC-5 cells and after UVB irradiation. ► C*HSDGIC* and PACAP promoted the proliferation of RGC-5 cells. ► C*HSDGIC* pretreatment attenuates UVB-induced apoptosis in RGC-5 cells.