C-terminal FGF23 is a strong predictor of survival in systolic heart failure

► Fibroblast growth factor 23 is an important of phosphate and calcium metabolism. ► C-terminal FGF23 is a 71 amino acids peptide. ► We have evaluated Ct-FGF23 in patients presenting systolic heart failure. ► Ct-FGF23 levels were markedly increased in HF patients. ► Ct-FGF23 is the strongest predictor of long term CV death.