Cigarette smoke-induced kinin B1 receptor promotes NADPH oxidase activity in cultured human alveolar epithelial cells

► Upregulation of kinin B1 receptor (B1R) and interleukin-1β. ► Enhanced superoxide anion production. ► Prevention of B1R induction and oxidative stress by NADPH oxidase inhibitors. ► Enhanced superoxide anion production by B1R activation.