RYH: A minimal peptidic sequence obtained from beta-chain hemoglobin exhibiting an antimicrobial activity

► Peptides derived from β114-145 exhibit antibacterial activity. ► The most active peptide is the shortest one: β140-145. ► Minimal antimicrobial sequence from beta-chain: RYH. ► These active peptides were able to interact with cellular membrane. ► Minimum antimicrobial sequence: Y, R and one positively charged amino acid.