Wound healing activity of the human antimicrobial peptide LL37

► Recombinant LL37 inhibits activation of macrophages by LPS. ► Recombinant LL37 induces proliferation, migration and tubule-like structures formation by endothelial cells in vitro. ► Topical application of LL37 improves wound healing through vascularization and re-epithelialization.