25-hydroxyvitamin D3 ameliorates periodontitis by modulating the expression of inflammation-associated factors in diabetic mice

► PTPN2 expression was studied in the diabetic gingival epithelium with periodontitis. ► 25(OH)D3 ameliorated diabetes with periodontitis through upregulating PTPN2. ► PTPN2 inhibited JAK1 phosphorylation in the gingival epithelium.