Steroids from Dysoxylum grande (Meliaceae) leaves

► 8 natural steroids isolated from plant, Dysoxylumgrande, Meliaceae. ► New steroids named Grandol A to F (1 to 7) and 20S,24R-epoxy-7β,25-dihydroxy-3,4-secodammar-4(28)-en-3-oic acid (8). ► Two of the New steroids (Grandol A and B) gave moderate activity as acetylcholinesterase inhibitors.