Synthesis of 14′,15′-dehydro-ritterazine Y via reductive and oxidative functionalizations of hecogenin acetate

► A highly efficient synthesis of a bissteroidal pyrazine. ► Synthesis of a ritterazine Y analog via reductive and oxidative modifications of hecogenin acetate. ► Stereoselective formation of a steroidal spiroketal via alkoxy radical cyclization of primary alcohol.