Nodulisporisteriods A and B, the first 3,4-seco-4-methyl-progesteroids from Nodulisporium sp.

- A chemical investigation on the metabolites of Nodulisporium sp. was carried out.
- Compounds 1 and 2 are the first examples of 3,4-seco-4-methyl-progesteroids.
- A hypothetical biosynthetic pathway for 1 and 2 has been proposed.
- It is the first report about the viridins with activity against Aβ42 aggregation.