Neohesperidin dihydrochalcone: Presentation of a small molecule activator of mammalian alpha-amylase as an allosteric effector

► Neohesperidin dihydrochalcone activates mammalian alpha-amylase up to threefold. ► This compound is a non-essential activator of alpha-amylase. ► Its putative interaction site is located on the N-terminal of the enzyme.