کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10871022 1074032 2013 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Protein dynamics in living cells studied by in-cell NMR spectroscopy
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک دانش گیاه شناسی
پیش نمایش صفحه اول مقاله
Protein dynamics in living cells studied by in-cell NMR spectroscopy
چکیده انگلیسی
Most proteins function in cells where protein concentrations can reach 400 g/l. However, most quantitative studies of protein properties are performed in idealized, dilute conditions. Recently developed in-cell NMR techniques can provide protein structure and other biophysical properties inside living cells at atomic resolution. Here we review how protein dynamics, including global and internal motions have been characterized by in-cell NMR, and then discuss the remaining challenges and future directions.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: FEBS Letters - Volume 587, Issue 8, 17 April 2013, Pages 1008-1011
نویسندگان
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