Signaling regulated endocytosis and exocytosis lead to mating pheromone concentration dependent morphologies in yeast

► Developed a mathematical model of membrane deformation coupled to cellular membrane signaling. ► Signaling mediated membrane velocity captures yeast budding and shmoo morphologies. ► Yeast mating projection morphology is inversely related to pheromone concentration. ► Morphology is the result of signaling induced balance of endocytosis and exocytosis.