کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10871620 1074064 2012 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Protein translocation as a tool: The current rapamycin story
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک دانش گیاه شناسی
پیش نمایش صفحه اول مقاله
Protein translocation as a tool: The current rapamycin story
چکیده انگلیسی
In cell biology and pharmacology, small chemicals are mostly used as agonists and antagonists against receptors and enzymes. The immunosuppressant rapamycin can serve an entirely different purpose: if employed sensibly, it might function as an inducer of dimerization that is able to rapidly activate enzyme activity inside the intact cell. A number of very recent developments such as photoactivatable derivatives make rapamycin an even more attractive tool for basic science.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: FEBS Letters - Volume 586, Issue 15, 16 July 2012, Pages 2097-2105
نویسندگان
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