کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10872236 | 1074111 | 2010 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Duality of the carbohydrate-recognition system of Pseudomonas aeruginosa-II lectin (PA-IIL)
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
دانش گیاه شناسی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Duality of the carbohydrate-recognition system of Pseudomonas aeruginosa-II lectin (PA-IIL) Duality of the carbohydrate-recognition system of Pseudomonas aeruginosa-II lectin (PA-IIL)](/preview/png/10872236.png)
چکیده انگلیسی
The study of Pseudomonas aeruginosa-II lectin (PA-IIL) complexes with Man derivatives as a recognition factor has been neglected since its monomer is a very weak ligand. Here, the roles of Man oligomers and complexes in PA-IIL carbohydrate-recognition were studied by both enzyme-linked lectinosorbent and inhibition assays. From the results obtained, it is proposed that high density weak -OH conformation as seen in yeast mannan is also an important PA-IIL recognition factor. This finding provides a peculiar concept of the duality of PA-IIL recognition system for lFucα1â and related complexes and for high density Manα1â complexes present in polymannosylated target macromolecules.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: FEBS Letters - Volume 584, Issue 11, 3 June 2010, Pages 2371-2375
Journal: FEBS Letters - Volume 584, Issue 11, 3 June 2010, Pages 2371-2375
نویسندگان
Albert M. Wu, Yu-Ping Gong, Chia-Chen Li, Nechama Gilboa-Garber,