کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10873957 1074288 2005 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
From proteomic inventory to architecture
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک دانش گیاه شناسی
پیش نمایش صفحه اول مقاله
From proteomic inventory to architecture
چکیده انگلیسی
Electron tomography can provide three-dimensional reconstructions of large pleomorphic structures at molecular resolution. While the principles of electron tomography have been known for decades, its use has gathered momentum only in recent years. Technological advances have made it possible to apply it to ice-embedded biological material (cryotomography), thereby ensuring a close-to-life preservation of the samples. In combination with advanced computational methods, such as molecular identification based on pattern recognition, it is a promising approach to comprehensively map macromolecular architecture inside organelles and cells and to visualize macromolecules at work in their natural environment.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: FEBS Letters - Volume 579, Issue 4, 7 February 2005, Pages 933-937
نویسندگان
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