Cytotoxicity of yessotoxin and okadaic acid in mouse T lymphocyte cell line EL-4

► YTX and OA have a potent and differential cytotoxic action on EL-4 cells. ► Toxicity by YTX or OA involved typical hallmarks of apoptosis. ► EL-4 T lymphocyte cell line is more susceptible to YTX exposure than to OA. ► Human health risk related to chronic exposure to low amounts of OA or YTX.