Proteomic profiling of dog urine after European adder (Vipera berus berus) envenomation by two-dimensional difference gel electrophoresis

► Envenomation by Vipera berus berus causes changes in urine protein profile in dogs. ► AAT, b2MG, albumin, fetuin-B and SOD1 were upregulated. ► The excreted AAT, b2MG and albumin are associated earlier with tubular injury. ► Origin of fetuin-B and SOD1 in dog urine after envenomation needs more studies.