Angiotensin-degrading serine peptidase: A new chymotrypsin-like activity in the venom of Bothrops jararaca partially blocked by the commercial antivenom

► Two FRETs peptides can be used as specific tolls for metallo and serine peptidases present in the Bothrops jararaca venom. ► The angiotensin I and dynorphin 1-13 are good substrates for the serine peptidases. ► The cleavage point in angiotensin I shows a new chymotrypsin-like activity in the venom of B. jararaca. ► These activities are partially blocked by the commercial antivenom produced by Instituto Butantan.