Keywords: Snake venom; Intraspecific venom variability; Bothrops jararaca; Captivity maintenance; Venom composition; Antivenom;
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Keywords: Venom gland; Primary culture; Toxin synthesis; Toxin secretion; Noradrenaline; Secretome; Bothrops jararaca;
Bradykinin-potentiating PEPTIDE-10C, an argininosuccinate synthetase activator, protects against H2O2-induced oxidative stress in SH-SY5Y neuroblastoma cells
Keywords: Bradykinin-potentiating peptides; Argininosuccinate synthase; Neuroprotection; Oxidative stress; Bothrops jararaca;
Bothrops jararaca accessory venom gland is an ancillary source of toxins to the snake
Keywords: Accessory gland; Proteomics; Transcriptomics; Toxins; Bothrops jararaca; Snake;
BjSP, a novel serine protease from Bothrops jararaca snake venom that degrades fibrinogen without forming fibrin clots
Keywords: Snake venom; Bothrops jararaca; Serine protease; Coagulation; Fibrinogen;
Development of IgY antibodies against anti-snake toxins endowed with highly lethal neutralizing activity
Keywords: Fab; antigen-binding fragment; F(abâ²)2; double antigen-binding fragment; IgG; mammalian immunoglobulin G; IgY; avian immunoglobulin Y; CS; complement system; Ba; Bitis arietans; Bj; Bothrops jararaca; Cdt; Crotalus durissus terrificus; BSA; bovine serum
Investigating possible biological targets of Bj-CRP, the first cysteine-rich secretory protein (CRISP) isolated from Bothrops jararaca snake venom
Keywords: Bothrops jararaca; CRISPs; Bj-CRP; Inflammation; Complement system; Ion channels;
An in-depth snake venom proteopeptidome characterization: Benchmarking Bothrops jararaca
Keywords: Bothrops jararaca; Cryptome; OFFGEL; Proteopeptidome; Proteomics; Snake venomics;
Combined venomics, venom gland transcriptomics, bioactivities, and antivenomics of two Bothrops jararaca populations from geographic isolated regions within the Brazilian Atlantic rainforest
Keywords: Snake venom proteomics; Venom gland transcriptomics; Antivenomics; Geographic venom variation; Bothrops jararaca
Jararhagin-induced mechanical hyperalgesia depends on TNF-α, IL-1β and NFκB in mice
Keywords: Bothrops jararaca; Jararhagin; Metalloprotease; Cytokines; Hyperalgesia; NFκB;
Malformations in Neotropical Viperids: Qualitative and Quantitative Analysis
Keywords: Bothrops jararaca; congenital anomalies; Crotalus durissus; snake
Proline rich-oligopeptides: Diverse mechanisms for antihypertensive action
Keywords: ACE; angiotensin I-converting enzyme; ASS; argininosuccinate synthetase; Bj; Bothrops jararaca; BK; bradykinin; PRO; proline-rich oligopeptide; ([Ca2+]i); intracellular calcium concentration; CNP; C-type natriuretic peptide; CNS; central nervous system; H
Angiotensin-degrading serine peptidase: A new chymotrypsin-like activity in the venom of Bothrops jararaca partially blocked by the commercial antivenom
Keywords: Bothrops jararaca; Angiotensin I; Serine peptidases; Antivenom; Neglected disease;
Morphological study of accessory gland of Bothrops jararaca and its secretory cycle
Keywords: Accessory gland; Secretory cycle; Venom; Bothrops jararaca; Snake
BJ-PI2, A non-hemorrhagic metalloproteinase from Bothrops jararaca snake venom
Keywords: Bothrops jararaca; Coagulopathy; Hemorrhage; Myonecrosis; Snake venom metalloproteinase (SVMP); Vascular permeability;
Bj-PRO-5a, a natural angiotensin-converting enzyme inhibitor, promotes vasodilatation mediated by both bradykinin B2 and M1 muscarinic acetylcholine receptors
Keywords: ACE; angiotensin-converting enzyme; ASS; argininosuccinate synthase; Bj; Bothrops jararaca; BK; bradykinin; BPPs; bradykinin-potentiating peptides; Bj-PROs; proline-rich oligopeptides from the venom glands of Bothrops jararaca venom glands; HEK; human emb
Immunome and venome of Bothrops jararacussu: A proteomic approach to study the molecular immunology of snake toxins
Keywords: Bothrops jararacussu; Bothrops jararaca; Crotalus durissus; Snake venom proteome; Immunome2D-PAGE, Two-dimensional gel electrophoresis; BthTx-I, Bothropstoxin-I; CRVP, Cysteine-rich snake venom proteins; CTL, C-type lectins; LAO, L-amino-acid oxidase; PLA
Bothrops jararaca antithrombin: Isolation, characterization and comparison with other animal antithrombins
Keywords: Antithrombin; Serpin; Amino acid sequence; Snake plasma; Bothrops jararaca
Effects of three vasoactive peptides isolated from the plasma of the snake Bothrops jararaca
Keywords: Vasoactive peptides; Bothrops jararaca; Blood pressure; Snake; Peptides
Proteomic profiling of snake venom metalloproteinases (SVMPs): Insights into venom induced pathology
Keywords: Bothrops jararaca; Bothrops lanceolatus; Snake venom; SVMP; Metalloproteases; Proteome
Antigenic, microbicidal and antiparasitic properties of an l-amino acid oxidase isolated from Bothrops jararaca snake venom
Keywords: Bothrops jararaca; l-Amino acid oxidase; Microbicidal; Leishmanicidal; Neutralizing potency
Bothrops jararaca fibrinogen and its resistance to hydrolysis evoked by snake venoms
Keywords: Bothrops jararaca; Blood coagulation; Fibrinogen; Reptiles; Snake plasma
Identification of proteins similar to Bothrops jararaca coagulation inhibitor (BjI) in the plasmas of Bothrops alternatus, Bothrops jararacussu and Crotalus durissus terrificus snakes
Keywords: Blood coagulation; Snake; Plasma; Bothrops jararaca; Thrombin inhibitor; Viperidae; Crotalinae
Characterization of urinary metabolites from four synthetic bradykinin potentiating peptides (BPPs) in mice
Keywords: Biotransformation; Bothrops jararaca; Proline-rich peptides; Angiotensin-converting enzyme inhibitors; Anti-hypertensive; Bradykinin potentiating peptidesAng, angiotensin; NEP, neprilysin (EC 3.4.24.11); TFA, trifluoroacetic acid; ACN, acetonitrile; i.v.,
Differences in endothelin receptor types in the vasculature of Bothrops jararaca (Viperidae) and Oxyrhopus guibei (Colubridae) snakes
Keywords: Ach; acetylcholine; AI; angiotensin I; Bj; Bothrops jararaca or B. jararaca; CCRC; cumulative concentration-response curve; ETA; endothelin receptor type A; ETB; endothelin receptor type B; ETs; endothelins; ET-1; endothelin-1; Emax; maximum effect; l-N
Predictors of Bothrops jararaca venom allergy in snake handlers and snake venom handlers
Keywords: Bothrops jararaca; Snake handler; Snake venom; Allergy; Immunoglobulin E.
Tissue distribution in mice of BPP 10c, a potent proline-rich anti-hypertensive peptide of Bothrops jararaca
Keywords: Bothrops jararaca; Proline-rich peptides; Angiotensin-converting enzyme inhibitors; Biodistribution; InternalizationAng-I, angiotensin I; Ang-II, angiotensin II; BK, bradykinin; Bj, Bothrops jararaca; ESI-MS, electrospray ionization-mass spectrometry; [12
Purification and functional characterization of bothrojaractivase, a prothrombin-activating metalloproteinase isolated from Bothrops jararaca snake venom
Keywords: Bothrops jararaca; Snake venom; Prothrombin activator; Metalloproteinase; Bleeding disorders; HemostasisTris–HCl, tris(hydroxymethyl)aminomethane hydrochloride; PMSF, phenylmethanesulfonyl fluoride; E-64, trans-epoxysuccinyl-l-leucylamido(4-guanidino)-but
Role of cyclooxygenases in oedema-forming activity of bothropic venoms
Keywords: Bothrops asper; Bothrops jararaca; Cyclooxygenase; Inflammation; COX-2; PGE2BaV, Bothrops asper venom; BjV, Bothrops jararaca venom; COX, cyclooxygenase; PG, prostaglandin
Novel pharmaceutical composition of bradykinin potentiating penta peptide with β-cyclodextrin: Physical–chemical characterization and anti-hypertensive evaluation
Keywords: Bothrops jararaca; Bradykinin potentiating peptides; ACE inhibitors; Anti-hypertensive activity; β-Cyclodextrin
Characterization and cDNA cloning of aminopeptidase A from the venom of Gloydius blomhoffi brevicaudus
Keywords: cDNA; Aminopeptidase A; Gloydius blomhoffi brevicaudus; Gloydius halys blomhoffii; Trimeresurus flavoviridis; Bothrops jararaca; Crotalus atrox; Snake venomAPA, Aminopeptidase A; APB, Aminopeptidase B; APN, Aminopeptidase N; DPP, Dipeptidyl peptidase; MCA
Enzymatic and immunochemical characterization of Bothrops insularis venom and its neutralization by polyspecific Bothrops antivenom
Keywords: Bothrops; Snake venom; Polyspecific Bothrops antivenom; Bothrops insularis; Bothrops jararaca; Microcirculation
Spectroscopic studies of stratum corneum model membrane from Bothrops jararaca treated with cationic surfactant
Keywords: FT-Raman; PAS-FTIR; Cetyl trimethyl ammonium chloride; Model membrane; Bothrops jararaca
A natural carrier effect and the generation of specific antibodies to biologically active peptides
Keywords: Antipeptide antibodies; Bradykinin-potentiating peptide; Carrier protein; High-responder mice; Bothrops jararaca;
Venom production in long-term primary culture of secretory cells of the Bothrops jararaca venom gland
Keywords: Secretory cells; Long-term culture; Venom production; Snake; Bothrops jararaca
Sexual dimorphism in venom of Bothrops jararaca(Serpentes: Viperidae)
Keywords: Snake size growth; Sexual dimorphism; Venom; Bothrops jararaca
Hemorphin and hemorphin-like peptides isolated from dog pancreas and sheep brain are able to potentiate bradykinin activity in vivo
Keywords: ACE; angiotensin-I converting enzyme; B.j.; Bothrops jararaca; BK; bradykinin; Ang I; angiotensin I; Ang II; angiotensin II; H-Pro-2ClTrT-resin; l-Proline-2-chlorotrityl resin; HPLC; high-performance liquid chromatography; TFA; trifluoroacetic acid; ACN;
Comparison of indirect and direct approaches using ion-trap and Fourier transform ion cyclotron resonance mass spectrometry for exploring viperid venom proteomes
Keywords: Snake venom proteomics; Mass spectrometry; Crotalus atrox; Bothrops jararaca
Evaluation of the effect of aqueous extract of Croton urucurana Baillon (Euphorbiaceae) on the hemorrhagic activity induced by the venom of Bothrops jararaca, using new techniques to quantify hemorrhagic activity in rat skin
Keywords: Bothrops jararaca; Croton urucurana; Hemorrhagic activity; Anti-venom;
Purification and characterization of a novel peptide with antifungal activity from Bothrops jararaca venom
Keywords: Antimicrobial peptides; Bothrops jararaca; Snake venom; Fungi inhibition;
Primary structure and antiplatelet mechanism of a snake venom metalloproteinase, acurhagin, from Agkistrodon acutus venom
Keywords: Acurhagin; Metalloproteinase; Agkistrodon acutus; Disintegrin; Glycoprotein VI; A. acutus; Agkistrodon acutus; B. arietans; Bitis arietans; B. jararaca; Bothrops jararaca; FcRγ; Fc receptor γ-chain; GP; glycoprotein; LAT; linker for activation of T cell