BJ-PI2, A non-hemorrhagic metalloproteinase from Bothrops jararaca snake venom

► Bothrops jararaca venom contains snake venom metalloproteinases (SVMPs). ► BJ-PI2 is a non-hemorrhagic, non-myotoxic, non-coagulant class P-I SVMP. ► BJ-PI2 increases vascular permeability and causes inflammatory cell migration. ► BJ-PI2 may contribute to venom-induced vascular permeability and inflammation.