کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10900586 | 1084653 | 2005 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Lymphotoxin-α polymorphism and the risk of cervical cancer in Japanese subjects
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
تحقیقات سرطان
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Lymphotoxin-α polymorphism and the risk of cervical cancer in Japanese subjects Lymphotoxin-α polymorphism and the risk of cervical cancer in Japanese subjects](/preview/png/10900586.png)
چکیده انگلیسی
To examine the possible association between cervical cancer and Lymphotoxin-α (LTα) polymorphisms, C804A and A252G, an incident case-control study was conducted in Japanese. The cases were 131 cervical cancer patients. Controls were 320 healthy women. Risk estimation was conducted by an unconditional logistic model. Complete linkage disequilibrium was seen between LTα C804A and LTα A252G. We found that, compared with the 804CC genotype, 804CA and 804AA were associated with a decreased risk of cervical cancer (OR=0.64, 95% CI=0.40-1.02; and OR=0.45, 95% CI=0.21-0.95, respectively), especially of SCC (OR=0.54, 95% CI=0.32-0.91; and OR=0.39, 95% CI=0.16-0.92, respectively).
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Cancer Letters - Volume 218, Issue 1, 31 January 2005, Pages 63-68
Journal: Cancer Letters - Volume 218, Issue 1, 31 January 2005, Pages 63-68
نویسندگان
Yoshimitsu Niwa, Kaoru Hirose, Keitaro Matsuo, Kazuo Tajima, Yoko Ikoma, Toru Nakanishi, Akihiro Nawa, Kazuo Kuzuya, Akiko Tamakoshi, Nobuyuki Hamajima,