Intra-bone marrow transplantation facilitates pauci-clonal human hematopoietic repopulation of NOD/SCID/β2m−/− mice

IBMT into NOD/SCID/β2m−/− mice provides a highly sensitive experimental transplantation assay for the detection of human hematopoietic repopulating cells and demonstrates that Lin−CD34+CD38− cells are more highly enriched for human SRC than originally predicted.