A paradoxical role for IFN-γ in the immune properties of mesenchymal stem cells during viral challenge

The results show a facilitating role of IFN-γ on CTL responses, although paradoxical in light of the veto properties of MSC. This report shows that in cases where MSC are used in transplantation for repair of damaged tissue, they can exert an additional role by protecting the host to viral challenges and thereby protect from its immunosuppressive properties.