Liposome-bound TRAIL induces superior DR5 clustering and enhanced DISC recruitment in histiocytic lymphoma U937 cells

- Liposomes with TRAIL show greater cytotoxicity than soluble TRAIL in leukemic cells.
- Liposomes with TRAIL induce a more efficient clustering of DR5 which is responsible for their higher activity.
- Liposomes with TRAIL induce a more potent DISC recruitment than soluble TRAIL.