کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10908785 1087808 2013 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Multiple myeloma-induced hyperammonemic encephalopathy: An entity associated with high in-patient mortality
ترجمه فارسی عنوان
آنسفالوپاتی هیپامامونمی ناشی از چندین بیماری میلوما: یک نهاد مرتبط با مرگ و میر بالای بیمار
کلمات کلیدی
میلوما، آمونیاک انسفالوپاتی،
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی تحقیقات سرطان
چکیده انگلیسی
Hyperammonemia attributed to multiple myeloma (MM) has been rarely reported. We present 6 patients from our institution and 34 from the literature with MM-induced hyperammonemic encephalopathy. The median age was 67 years with male:female ratio of 1.8:1. The median ammonia level was 114 umol/L. IgG and IgA MM was seen in 40% and 35% of cases, respectively. The in-patient mortality was 48%. The in-patient mortality was 31% in patients who received MM-directed therapy and 100% in those who did not received MM-directed therapy. Hyperammonemic encephalopathy is a rare complication in MM and is associated with high in-patient mortality.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Leukemia Research - Volume 37, Issue 10, October 2013, Pages 1229-1232
نویسندگان
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