کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10909573 | 1087920 | 2005 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Potential and origin of the hematopoietic population in human skeletal muscle
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
تحقیقات سرطان
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چکیده انگلیسی
While mononuclear cells isolated from murine skeletal muscle were shown to be capable of hematopoietic activity, similar hematopoietic cells (HC) recently were reported to exist in primate muscle. We investigated muscle-derived HC from young and adult human subjects. Although hematopoietic stem cells were rare in muscle, their frequency nonetheless was approximately four times greater than in peripheral blood. These cells in muscle appeared to originate from CD45+ bone marrow cells. Our results suggested an additional function of human skeletal muscle as a reservoir of HC.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Leukemia Research - Volume 29, Issue 3, March 2005, Pages 317-324
Journal: Leukemia Research - Volume 29, Issue 3, March 2005, Pages 317-324
نویسندگان
Kosuke Tsuboi, Hiroshi Kawada, Eiren Toh, Yoon Hwan Lee, Mitsuyo Tsuma, Yoshihiko Nakamura, Tadayuki Sato, Kiyoshi Ando, Joji Mochida, Shunichi Kato, Tomomitsu Hotta,