کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10909588 1087925 2005 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
High Th1/Th2 ratio in patients with multiple myeloma
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی تحقیقات سرطان
پیش نمایش صفحه اول مقاله
High Th1/Th2 ratio in patients with multiple myeloma
چکیده انگلیسی
To determine the clinical significance of the T helper 1(Th1)/T helper 2 (Th2) ratio in multiple myeloma, the intracellular IFN-γ and IL-4 were analyzed by flow cytometry in 56 patients with multiple myeloma. The mean Th1/Th2 ratio of cases in the initial diagnosis phase and the refractory phase were higher than that of the control group. The mean serum beta-2-microglobulin in the high Th1/Th2 subgroup was significantly higher than that in the normal Th1/Th2 subgroup (P < 0.05). In conclusion, the Th1/Th2 ratio was closely related to the disease status of multiple myeloma.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Leukemia Research - Volume 29, Issue 2, February 2005, Pages 135-140
نویسندگان
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