کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10911340 1088292 2012 18 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The challenge of NSCLC diagnosis and predictive analysis on small samples. Practical approach of a working group
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی تحقیقات سرطان
پیش نمایش صفحه اول مقاله
The challenge of NSCLC diagnosis and predictive analysis on small samples. Practical approach of a working group
چکیده انگلیسی
► The diagnosis of lung cancer involves the identification and complete classification of malignancy. ► New therapeutic options require specific subtyping of NSCLCs and, increasingly, the identification of therapeutically predictive molecular markers, to determine the safest and most effective choice of drugs. ► Small diagnostic sample size and tumour complexity often prevent specific subtyping on morphological grounds alone (NSCLC-NOS). ► Immunohistochemistry can predict the likely NSCLC subtype (squamous cell vs. adenocarcinoma) in most NSCLC-NOS cases. ► Tissue sampling should be maximized whenever feasible and deemed clinically safe, reducing the need for re-biopsy for additional studies. ► Tissue handling, processing and sectioning should minimize wastage and optimize use of tissue for diagnosis.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Lung Cancer - Volume 76, Issue 1, April 2012, Pages 1-18
نویسندگان
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