Feasibility of applying a single treatment plan for both fractions in PDR image guided brachytherapy in cervix cancer

For IC BT in small volume tumours (primarily stage IB-IIB) with mean HR CTV volume at BT1 = 24 ± 12 cm3, comparable mean DVH parameters resulted when applying a single plan, but with considerable variations in individual patients. Yet since in our population the applied target doses are high and the OARs doses are lower than the dose volume constraints these variations may not have considerable clinical consequences. Individual optimisation for each BT fraction is recommended when interstitial needles are used.