Developmental changes in the expression and function of TRPC6 channels related the F-actin organization during differentiation in podocytes

- The distribution of TRPC6 channels changes with podocyte differentiation.
- TRPC6 currents undergo developmental changes during podocyte differentiation.
- TRPC6 inhibition leads to F-actin rearrangement only on the developmental stage.
- TPRC6 is required for development of glomerulus.