Lipid body accumulation alters calcium signaling dynamics in immune cells

- Obesity and hyperinsulinemia are significant health burdens globally.
- Lipid body accumulation at the cellular level characterizes these disorders.
- The effect of lipid body accumulation on transcytoplasmic signal transduction is studied here.
- The presence of large numbers of lipid bodies alters calcium-signaling dynamics in the cytoplasm of an immunocyte.