کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10927081 1092328 2012 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Dendritic cells transduced with lentiviral vector targeting RelB gene using RNA interference induce hyporesponsiveness in memory CD4+ T cells and naïve CD4+ T cells
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیولوژی سلول
پیش نمایش صفحه اول مقاله
Dendritic cells transduced with lentiviral vector targeting RelB gene using RNA interference induce hyporesponsiveness in memory CD4+ T cells and naïve CD4+ T cells
چکیده انگلیسی
► DCs transduced with lentiviral vector targeting RelB using RNAi (DCs-miR RelB) were resistant to maturation induction. ► DCs-miR RelB could induce Ag specific hyporesponsiveness in TNs and non-Ag specific hyporesponsiveness in TMs. ► An alter patter of miR-181a induced by DCs-miR RelB could be associated with the proliferation of TNs and TMs. ► An alter patter of miR-155 induced by DCs-miR RelB could be associated with the cytokine secretion of TNs and TMs. ► DCs-miR RelB significantly reduced the intracellular Ca2+ level of TNs and TMs.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Cellular Immunology - Volume 273, Issue 1, 2012, Pages 85-93
نویسندگان
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