کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10927659 | 1092881 | 2016 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
The safety and efficacy of bladder cryoablation in a beagle model by using a novel balloon cryoprobe
ترجمه فارسی عنوان
ایمنی و کارآیی کریوابلاسیون مثانه در مدل کایگل با استفاده از کریوپروب بالون جدید
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موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
علوم کشاورزی و بیولوژیک (عمومی)
چکیده انگلیسی
The poor quality of initial transurethral resection (TUR) would leave residual tumor and compromise the prognosis. The common therapeutic option is to perform re-TUR, which adds burden to patients. We assumed that cryoablation could be applied as adjuvant therapy combined with TUR, thus lead to maxium tumor control. In our study, we investigated the safety and effects of focal bladder wall cryoablation in beagle model using a novel cryoablation balloon probe. Temperature was recorded throughout the freeze process in different parts of the bladder. The bladder was harvested immediately, 2 weeks or 3 months after surgery for histological evaluation. The results demonstrated cryoablation using our newly designed probe is safe and effective. Two-minute cryoablation could induce necrosis within 2-cm range in diameter to superficial muscle layer. The findings provided us reference before cryoablation could be applied in clinical practice.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Cryobiology - Volume 72, Issue 2, April 2016, Pages 157-160
Journal: Cryobiology - Volume 72, Issue 2, April 2016, Pages 157-160
نویسندگان
Shenghua Liu, Lujia Zou, Shanhua Mao, Limin Zhang, Hua Xu, Tian Yang, Haowen Jiang, Qiang Ding,