Moderate hypothermia initiated during oxygen-glucose deprivation preserves HL-1 cardiomyocytes

Moderate TH initiated during OGD is a promising intervention for the protection of cardiomyocytes from OGD/R-induced injury. The attenuation of mitochondrial dysfunction and apoptosis by intra-OGD cooling are beneficial effects of hypothermia-induced cardioprotection, resulting in minimized myocardial cell death after OGD and OGD-R-induced injuries.