کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10928028 1092890 2014 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Percutaneous cryotherapy for metastatic bladder cancer: Experience with 23 patients
ترجمه فارسی عنوان
سرماخوردگی پوستی برای سرطان مثانه متاستاتیک: تجربه با 23 بیمار
کلمات کلیدی
سرطان مثانه متاستاتیک، کریوآبلودی پوستی بقا بدون پیشرفت،
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم کشاورزی و بیولوژیک (عمومی)
چکیده انگلیسی
Bladder cancer is the most common malignancy of the urinary tract and in many patients is metastatic at diagnosis. Chemotherapy is the standard treatment for these patients but has serious side effects and in many patients is not tolerated. To avoid the side effects of systemic chemotherapy, patients with late stage bladder cancer have sought cryotherapy in our hospital. We reviewed data for the past 4 years to evaluate the safety and efficiency of percutaneous cryotherapy in 23 patients. Within 3 days after cryosurgery, all complications of bladder cancer (e.g. hematuria, urinary irritation, hypogastralgia, lumbago) had decreased to some degree. No new complications (e.g. bladder perforation) occurred and all complications had disappeared completely after 2 weeks. The progression-free survival (PFS) of these patients was 14 ± 8 months. There was no effect on PFS of tumor location or histopathology; however, differentiation status and tumor size influenced the therapeutic effect of percutaneous cryoablation. In conclusion, percutaneous cryotherapy may be a safe and efficacious therapeutic option in the treatment of metastatic bladder cancer.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Cryobiology - Volume 68, Issue 1, February 2014, Pages 79-83
نویسندگان
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