The transcriptional regulator lola is required for stem cell maintenance and germ cell differentiation in the Drosophila testis

► lola is required cell autonomously for Drosophila male germline stem cell maintenance. ► lola is required cell autonomously for somatic cyst stem cell maintenance. ► lola restricts proliferation of transit amplifying spermatogonia. ► lola is required for meiotic cell cycle progression and spermatid differentiation. ► lola isoforms exhibit stage and cell type specific functions during spermatogenesis.