Semaphorin3d mediates Cx43-dependent phenotypes during fin regeneration

► Sema3d acts downstream of Cx43 during fin regeneration. ► Sema3d mediates Cx43-dependent cell proliferation and joint formation. ► Nrp2a is a putative Sema3d receptor that regulates cell proliferation. ► PlxnA3 is a putative Sema3d receptor that regulates joint formation.