Sgt1 acts via an LKB1/AMPK pathway to establish cortical polarity in larval neuroblasts

► We used a novel sequence-capture genomic method to identify sgt1. ► Sgt1 is required for Bazooka localization in neuroblasts. ► Sgt1 is required for Scribble localization in neuroblasts. ► Sgt1 acts at the top of an Hsp90-LKB1-AMPK polarity pathway.