Defective cranial skeletal development, larval lethality and haploinsufficiency in Myod mutant zebrafish

►Myod is a transcription factor that controls skeletal myogenesis. ►Myod is essential for most cranial myogenesis and viability in zebrafish. ►Lack of cranial muscle leads to cartilage and bone maturation defects in the head. ►Myod and Myf5 cooperate to drive all embryonic and larval myogenesis.