Reduced CD26 expression is associated with improved cardiac function after acute myocardial infarction

► After MI, increased mncCD26 expression is associated with decreased LV recovery. ► Increased mncCD26 is associated with decreased in vitro migration capacities. ► Inhibition of CD26 with sitagliptin improves in vitro homing capacities of MNCs. ► Early post MI treatment with sitagliptin may increase MNC homing to the infarct area.