Protein S-glutathiolation: Redox-sensitive regulation of protein function

► S-glutathiolation regulates cardiovascular function. ► S-glutathiolation protects protein thiols from irreversible oxidation. ► S-glutathiolation regulates intermediary metabolism and cell signaling. ► S-glutathiolation can maintain proteins in an encrypted state. ► Enzymes regulate the glutathiolation-deglutathiolation cycle.