Neuroinflammation and oxidative stress: Co-conspirators in the pathology of Parkinson's disease

► Neuroinflammation and oxidative stress have been implicated in neuronal loss in PD. ► A pro-inflammatory response has been identified in human PD patients. ► Genetic and toxin-based animal models have allowed a greater understanding of PD. ► Oxidative stress and neuroinflammation have been confirmed in mouse PD models.