Resveratrol preconditioning modulates inflammatory response in the rat hippocampus following global cerebral ischemia

► Resveratrol pretreatment decreased the expression of NF-κB and JNK levels. ► Resveratrol also ameliorated the elevated levels of substrate iNOS and COX-2. ► Resveratrol decreased astrocyte and microglial activation following global cerebral ischemia.