Endothelin/endothelin-B receptor signals regulate ventricle-directed interkinetic nuclear migration of cerebral cortical neural progenitors

► ETB-R is the highest expression level among GPCRs expressed in NPCs. ► ETB-R is a critical regulator of INM that precedes neurogenesis. ► ETB-R is a dual function receptor promoting both motility and adhesion of NPCs. ► ETB-R-mediated assembly signals drive INM that precedes neurogenesis.