Release of ATP from avian Müller glia cells in culture

▶ Quinacrine labels ATP-containing vesicles in Müller glia cells in culture. ▶ Glutamate induces an increase in extracellular ATP levels in these cultures. ▶ NMDA and non-NMDA receptors mediate the accumulation of extracellular ATP. ▶ Glutamate induces ATP release by a calcium-dependent exocytotic mechanism.