The α, β-unsaturated pyrazolone-based fluorescent sensor with red emission and its application for real-time monitoring hypochlorite in cancer cells and zebrafish

BODIPY-Pyra displayed a weak red emission because of rotation of α, β-unsaturated pyrazolone, which afforded the fluorescent change of BODIPY-Pyra by the chemical reaction. Moreover, it could monitor the intracellular hypochlorite in cancer cells and endogenous hypochlorite in living zebrafish without drug induction.161