کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
11027713 | 1666162 | 2019 | 24 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Use of experimental-resin-based materials doped with carboxymethyl chitosan and calcium phosphate microfillers to induce biomimetic remineralization of caries-affected dentin
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موضوعات مرتبط
مهندسی و علوم پایه
سایر رشته های مهندسی
مهندسی پزشکی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
This study investigated carboxymethyl chitosan (CMC)-induced biomimetic mineralization of collagen fibrils, with the aim of synthesizing experimental resins doped with CMC and calcium phosphate microfillers to remineralize artificial caries-affected dentin (ACAD) and enhance resin-dentin bonding durability. A size exclusion test provided evidence for the rejection of CMC (Mw 150â¯kDa) by collagen fibrils. Transmission electron microscopy and selected area electron diffraction conducted on reconstituted two-dimensional collagen showed typical deposition of needle-like hydroxyapatite crystals within collagen fibrils through CMC-induced biomimetic mineralization. The Vickers hardness test revealed significant improvement (Pâ¯<â¯0.001) of the hardness of ACAD treated with CMC-containing experimental resins. Confocal laser scanning microscopy showed reduced dentin permeability and defect sites after biomimetic mineralization. On microtensile bond strength testing, the CMC-remineralized ACAD had better bonding with resin than ACAD and traditionally remineralized ACAD in both self-etch and etch-and-rinse bonding modes (Pâ¯<â¯0.001). In conclusion, CMC is efficient in directing the biomimetic mineralization of collagen fibrils. The experimental resins containing CMC can induce dentin biomimetic remineralization and improve the bonding performance of ACAD.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of the Mechanical Behavior of Biomedical Materials - Volume 89, January 2019, Pages 81-88
Journal: Journal of the Mechanical Behavior of Biomedical Materials - Volume 89, January 2019, Pages 81-88
نویسندگان
Zihua Huang, Yipin Qi, Kai Zhang, Lisha Gu, Jiaxin Guo, Ruoxun Wang, Sui Mai,