کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
11029341 1646543 2018 11 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Circulating tumour DNA is a potential biomarker for disease progression and response to targeted therapy in advanced thyroid cancer
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی تحقیقات سرطان
پیش نمایش صفحه اول مقاله
Circulating tumour DNA is a potential biomarker for disease progression and response to targeted therapy in advanced thyroid cancer
چکیده انگلیسی
The majority of patients with advanced thyroid cancer had detectable ctDNA. ctDNA measurement may offer superiority over conventional markers in several scenarios: earlier detection of progression in MTC; as an alternative biomarker when conventional markers are not available; more rapid assessment of the disease status in response to targeted therapies, thereby potentially allowing prompter discontinuation of futile therapies. These early results support the hypothesis that ctDNA may be a clinically useful biomarker in thyroid cancer.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Cancer - Volume 103, November 2018, Pages 165-175
نویسندگان
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