کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
11458 742 2007 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Effects of solvent dehydration on creep resistance of poly(vinyl alcohol) hydrogel
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی بیو مهندسی (مهندسی زیستی)
پیش نمایش صفحه اول مقاله
Effects of solvent dehydration on creep resistance of poly(vinyl alcohol) hydrogel
چکیده انگلیسی

As a synthetic replacement material for osteochondral defect repair, poly(vinyl alcohol) (PVA) hydrogels offer a great potential due to their high water content and strong mechanical integrity. To survive the high stress environment in the joint space, high creep resistance becomes one of the key requirements for hydrogel implants. We hypothesized that reducing the equilibrium water content (EWC) of hydrogels would improve their creep resistance. We investigated the effect of dehydration of PVA theta-gels in various solvent/solution media followed by rehydration in saline solution. Decreasing EWC increased the creep resistance of PVA theta-gels. The most effective medium was isopropyl alcohol for reducing the EWC and increasing the creep resistance of PVA theta-gels.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biomaterials - Volume 28, Issue 5, February 2007, Pages 772–780
نویسندگان
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