کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1150733 957981 2006 17 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The doubly adaptive weighted differences design
موضوعات مرتبط
مهندسی و علوم پایه ریاضیات ریاضیات کاربردی
پیش نمایش صفحه اول مقاله
The doubly adaptive weighted differences design
چکیده انگلیسی
Allocation of subjects in clinical trials operates in the presence of two conflicting goals: the allocation procedure should limit the number of subjects allocated to the inferior treatment while simultaneously obtaining sufficient information from the subjects about the relative efficacies of the treatments. In this paper the doubly adaptive weighted differences design, which gives an explicit weight to each of the goals, is introduced and its theoretical properties are investigated. In addition, simulation results which assess the proportion of successes and the mean square error of estimators are given.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Statistical Planning and Inference - Volume 136, Issue 6, 1 June 2006, Pages 1923-1939
نویسندگان
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